Gros soucis défragmentation

Bonjour,
j'ai un ordi portable sur lequel il m'est imposible effectuer une défragmentation du disque dur
lorque je lance malwarebyte's,l'analyse se lance mais ne va pas au bout
pour ces 2 applications,mon ordi se bloque totalement,souris bloqué,clavier bloqué et je suis obligé de l'éteindre par le bouton marche,arrêt et de le redemarrer.
j'ai effectuer "cclearner""spybot""antivir" et rien
je joint un rapprt "hijackthis" si qql peut me renseigner
merci

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 15:34:10, on 04/02/2009
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16762)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Ahead\InCD\InCDsrv.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\ZoneLabs\vsmon.exe
C:\Program Files\Lavasoft\Ad-Aware\aawservice.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Avira\AntiVir PersonalEdition Classic\sched.exe
C:\Program Files\Avira\AntiVir PersonalEdition Classic\avguard.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\Program Files\Fichiers communs\Nero\Nero BackItUp 4\NBService.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = https://www.orange.fr/portail
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName = Liens
R3 - URLSearchHook: Yahoo! Toolbar avec bloqueur de fenêtres pop-up - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - (no file)
O2 - BHO: Adobe PDF Link Helper - {18DF081C-E8AD-4283-A596-FA578C2EBDC3} - C:\Program Files\Fichiers communs\Adobe\Acrobat\ActiveX\AcroIEHelperShim.dll
O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O2 - BHO: Programme d'aide de l'Assistant de connexion Windows Live - {9030D464-4C02-4ABF-8ECC-5164760863C6} - C:\Program Files\Fichiers communs\Microsoft Shared\Windows Live\WindowsLiveLogin.dll
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar1.dll
O2 - BHO: Google Toolbar Notifier BHO - {AF69DE43-7D58-4638-B6FA-CE66B5AD205D} - C:\Program Files\Google\GoogleToolbarNotifier\5.0.926.3450\swg.dll
O3 - Toolbar: Easy-WebPrint - {327C2873-E90D-4c37-AA9D-10AC9BABA46C} - C:\Program Files\Canon\Easy-WebPrint\Toolband.dll
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKUS\S-1-5-19\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\CTFMON.EXE (User 'SERVICE LOCAL')
O4 - HKUS\S-1-5-20\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\CTFMON.EXE (User 'SERVICE RÉSEAU')
O4 - HKUS\S-1-5-18\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\CTFMON.EXE (User 'SYSTEM')
O4 - HKUS\.DEFAULT\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\CTFMON.EXE (User 'Default user')
O9 - Extra button: Ajout Direct - {219C3416-8CB2-491a-A3C7-D9FCDDC9D600} - C:\Program Files\Windows Live\Writer\WriterBrowserExtension.dll
O9 - Extra 'Tools' menuitem: &Ajout Direct dans Windows Live Writer - {219C3416-8CB2-491a-A3C7-D9FCDDC9D600} - C:\Program Files\Windows Live\Writer\WriterBrowserExtension.dll
O9 - Extra button: Envoyer à OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\WINDOWS\system32\shdocvw.dll
O9 - Extra 'Tools' menuitem: &Envoyer à OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\WINDOWS\system32\shdocvw.dll
O9 - Extra button: Create Mobile Favorite - {2EAF5BB1-070F-11D3-9307-00C04FAE2D4F} - C:\PROGRA~1\MI3AA1~1\INetRepl.dll
O9 - Extra button: (no name) - {2EAF5BB2-070F-11D3-9307-00C04FAE2D4F} - C:\PROGRA~1\MI3AA1~1\INetRepl.dll
O9 - Extra 'Tools' menuitem: Créer un favori mobile... - {2EAF5BB2-070F-11D3-9307-00C04FAE2D4F} - C:\PROGRA~1\MI3AA1~1\INetRepl.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\WINDOWS\system32\shdocvw.dll
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O16 - DPF: {6F15128C-E66A-490C-B848-5000B5ABEEAC} (HP Download Manager) - https://h20436.www2.hp.com/ediags/dex/secure/HPDEXAXO.cab
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://fpdownload2.macromedia.com/get/shockwave/cabs/flash/swflash.cab
O23 - Service: Lavasoft Ad-Aware Service (aawservice) - Lavasoft - C:\Program Files\Lavasoft\Ad-Aware\aawservice.exe
O23 - Service: Avira AntiVir Personal - Free Antivirus Scheduler (AntiVirScheduler) - Avira GmbH - C:\Program Files\Avira\AntiVir PersonalEdition Classic\sched.exe
O23 - Service: Avira AntiVir Personal - Free Antivirus Guard (AntiVirService) - Avira GmbH - C:\Program Files\Avira\AntiVir PersonalEdition Classic\avguard.exe
O23 - Service: Ati HotKey Poller - Unknown owner - C:\WINDOWS\system32\Ati2evxx.exe
O23 - Service: getPlus(R) Helper - NOS Microsystems Ltd. - C:\Program Files\NOS\bin\getPlus_HelperSvc.exe
O23 - Service: Google Updater Service (gusvc) - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: InCD Helper (InCDsrv) - Ahead Software AG - C:\Program Files\Ahead\InCD\InCDsrv.exe
O23 - Service: Nero BackItUp Scheduler 4.0 - Nero AG - C:\Program Files\Fichiers communs\Nero\Nero BackItUp 4\NBService.exe
O23 - Service: ServiceLayer - Nokia. - C:\Program Files\PC Connectivity Solution\ServiceLayer.exe
O23 - Service: TuneUp Drive Defrag Service (TuneUp.Defrag) - TuneUp Software GmbH - C:\WINDOWS\System32\TuneUpDefragService.exe
O23 - Service: TrueVector Internet Monitor (vsmon) - Zone Labs, LLC - C:\WINDOWS\system32\ZoneLabs\vsmon.exe
O23 - Service: W3 Service Performance Counters (w3ctrs) - Unknown owner - rundll32.exe (file missing)